Reward and Punishment Sensitivity are Associated with Cross-disorder Traits

Reversal learning deficits following reward and punishment processing are observed across disruptive behaviors (DB) attention-deficit/hyperactivity disorder (ADHD), have been associated with callous-unemotional (CU) traits. However, it remains unknown to what extent these altered reinforcement sensitivities linked the co-occurrence of oppositional traits, ADHD symptoms, CU Reward sensitivity perseverative behavior were therefore derived from a probabilistic reversal task investigate in participants DB (n=183, ODD=62, CD=10, combined=57, age-range 8-18), (n=144, 11-28), controls (n=191, 8-26). The SNAP-IV Conners rating scales used assess Inventory traits was Decreased symptom severity (p=0.018) if corrected for symptoms. symptomatology interacted on perseveration (p=0.019), former aggravating effect vice versa. Within pooled sample, alterations underpinned by hyposensitivity increased perseveration. These results show as opposed is decreased reward-based adolescents adults.